26833-85-2：产品说明书

26833-85-2：产品说明书

                                                <a href="https://www.medchemexpress.com/Harringtonine.html">Harringtonine</a>产品描述：Harringtonine, a natural <i>Cephalotaxus</i> alkaloid, is an inhibitor of protein synthesis.<i><b>In Vitro:</b></i> Harringtonine inhibits the elongation phase of translation by preventing substrate binding to the acceptor site on the 60-S ribosome subunit and therefore block aminoacyl-tRNA binding and peptide bond formation^[1]. Harringtonine displays potent inhibition of Chikungunya virus infection with an EC₅₀ of 0.24 μM. Harringtonine could inhibit other alphaviruses^[2]. Harringtonine inhibits the growth of human myeloid leukemia cells <i>in vitro</i> at low concentrations. The mechanism of the antitumor action of harringtonine is considered to be an effect on protein synthesis and is characterized by breakdown of polysomes to monosomes^[3]. <br /><br /><br /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">公司介绍：MedChemExpress(MCE)专注于各种抑制剂、激动剂、API及化合物库，总部位于美国新泽西，分别在瑞典和上海设有欧洲区子公司和亚洲区总代理，营销网点遍及全球20多个国家地区。MCE经过多年努力已成为全球生物活性小分子领域的一流供应商， 产品涵盖癌症、神经科学、抗感染、表观遗传学等20个热门研究领域，PI3K、MAPK等近千个细分靶点，超过4000个活性小分子化合物现货，以及GPCR、API、离子通道等超过20种不同类型的化合物库，同时提供从毫克到千克的专业定制合成服务。</span><br style="color: rgb(62,62,62);" /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">MCE 对每批产品都进行严格的LCMS和NMR检验，其产品已被全球近万名客户广泛使用并发表大量文章、专利；</span><br style="color: rgb(62,62,62);" /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">MCE 定期增加各领域热门抑制剂、激动剂，不断扩增已有化合物库，以满足最新的科研需求；</span><br style="color: rgb(62,62,62);" /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">数千种产品在上海有充足备货，24-48小时内送达客户；</span><br style="color: rgb(62,62,62);" /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">大量产品提供免费试用装；</span><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">已为全球多个知名企业、院校构建各种定制型化合物库。</span><br /><br />产品链接：<a href="http://www.medchemexpress.cn/harringtonine.html">www.medchemexpress.cn/harringtonine.html</a><br /><br /><img alt=""  src="http://img.dxycdn.com/trademd/upload/userfiles/image/2014/08/A1408605159png_small.jpg" style="width: 600.0px;height: 310.0px;" />                                            </div>