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Docosatrienoic Acid研究进展

发布日期：2017-10-30   浏览次数：0
核心提示：a href=https://www.medchemexpress.com/Docosatrienoic_Acid.htmlDocosatrienoic Acid/a产品描述：Docosatrienoic acid is a ra
<a href="https://www.medchemexpress.com/Docosatrienoic_Acid.html">Docosatrienoic Acid</a>产品描述：Docosatrienoic acid is a rare ω-3 fatty acid; inhibits LTB4 binding to pig neutrophil membranes with an <b>K<sub>i</sub></b> of 5 μM.

IC50 & Target: Ki: 5 μM (LTB4)<sup>[1]</sup>

<i><b>In Vitro:</b></i> Docosatrienoic acid inhibits LTB4 binding to pig neutrophil membranes with an <b>K<sub>i</sub></b> of 5 μM<sup>[1]</sup>.

<i><b>In Vivo:</b></i> Application of docosatrienic acid  dose-dependently decreases the peak K<sup>+</sup> current amplitide and accelerates the potassium activation and inactivation kinetics at all rat membrane potentials<sup>[2]</sup>. <br><br>
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