Prostaglandin E2说明

Prostaglandin E2 是从前列腺分泌物中分离到的一种天然的血管扩张药，一般是通过结合并激活prostaglandin E2 receptor起作用。
Succinobucol产品描述：Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. In Vitro: Succinobucol (10, 50, 100 μM) causes a dose-dependent reduction in collagen-induced platelet aggregation in rabbit whole blood. Succinobucol also causes a significant reduction in whole blood aggregation in response to ADP. Succinobucol (10, 100 μM) significantly lowers the relaxation to X/XO^[1]. Succinobucol significantly prevents 3-NP-induced loss of SH-SY5Y cell viability, generation of reactive oxygen species, and decrease of ΔΨm. Succinobucol does not protect against 3-NP-induced inhibition of mitochondrial complex II activity, pointing to the mitigation of secondary events resultant from mitochondrial complex II inhibition. Succinobucol significantly increases (50 %) the levels of GSH in SH-SY5Y cells, which is paralleled by significant increases in glutamate cysteine ligase messenger RNA (mRNA) expression and activity^[2]. Succinobucol effectivel


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产品链接：www.medchemexpress.cn/Succinobucol.html


Purity:98%
MWt:352.4651
Formula:C20H32O5
SMILES:CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)C/C=C\CCCC(O)=O
Pathway:GPCR/G Protein;
Mechanisms:Prostaglandin Receptor;
Research Area:Cardiovascular Disease
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